Yes, you can run a vacuum cleaner with oxygen in the room. In fact, oxygen is a crucial component of the air we breathe, and it's present in the atmosphere at approximately 21% concentration. Vacuum cleaners are designed to be used in regular room conditions, and the presence of oxygen in the air is not a concern.
It's essential to have sufficient oxygen in any indoor environment to support human breathing and prevent the risk of asphyxiation. As long as you are in a typical room with good ventilation, there will be an ample supply of oxygen for both you and the vacuum cleaner to function safely.
However, it's worth noting that some vacuum cleaners can produce a small amount of dust and particles as they operate, especially if the vacuum has a bagless design. These particles can become airborne during vacuuming and may irritate individuals with respiratory sensitivities. To minimize this, ensure that your vacuum cleaner has appropriate filters and follow the manufacturer's instructions for maintenance and cleaning.
Overall, running a vacuum cleaner in a room with oxygen is safe and standard practice in any household cleaning routine.